PARACETAMOL

DID YOU KNOW THAT PARACETAMOL CAN KILL YOU!!

Patients who overdose on paracetamol can end up with Liver failure , Multi-organ Dysfunction or worse- End up in a Coffin!

PARACETAMOL TOXICITY CAN BE DIVIDED INTO 4 PHASES

PHASE 1

Patients may be asymptomatic or report anorexia, nausea or vomiting, and malaise
    Physical examination may reveal pallor, diaphoresis, malaise, and fatigue

    PHASE 2

   18-72 h after ingestion

    Patients generally develop right upper quadrant abdominal pain, anorexia, nausea, and vomiting
    Right upper quadrant tenderness may be present
    Tachycardia and hypotension indicate ongoing volume loss
   Some patients may report decreased urinary output (oliguria)
 
   PHASE 3

      72-96 h after ingestion

          Patients may have continued nausea and vomiting, abdominal pain, and a tender hepatic edge
          Hepatic necrosis and dysfunction are associated with jaundice, coagulopathy, hypoglycemia, and hepatic encephalopathy
          Acute renal failure develops in some critically ill patients
          Death from multi-organ failure may occur

   PHASE 4

             4 d to 3 wk after ingestion

        Patients who survive critical illness in phase 3 have complete resolution of symptoms and complete resolution of organ failure


SO, DO NOT TAKE ANT MEDICINE WITHOUT ADVICE FROM A COMPETENT DOCTOR!

Dr.Sheena